SL5MER_DMS_0001

SL5_MERS_GCadded

General
Reactivity heatmap for SL5MER_DMS_0001
Download .rdat

Construct

RMDB ID
SL5MER_DMS_0001
Name
SL5_MERS_GCadded
Sequence (206 nt)
GGGAACGACUCGAGUAGAGUCGAAAAGGAGCGUCGUGUCUCUUGUACGUCUCGGUCACAAUACACGGUUUCGUCCGGUGCGUGGCAAUUCGGGGCACAUCAUGUCUUUCGUGGCUGGUGUGACCGCGCAAGGUGCGCGCGGUACGUAUCGAGCAGCGCUCCAAAACAUUGCUCUUCGGAGCAAUGAAAAGAAACAACAACAACAAC
Structure
.....((((((.....))))))....(((((((..((.(((..(((((((((((((((..(((.(((......)))))).)))))....)))).(((((((.(((......))))))))))(((((((.......))))))))))))).))))))))))))....((((((((....)))))))).....................
Offset
178
# of constructs
136
# of data points
21760
Last modified
07/28/24
Version
1
Owner
rui huang

Comments

Output of UBR
from data: RH_NovaSeq_2023_06_06_SL5_M2seq
Mutational Profiling
Library ordered from Agilent, standard synthesis

Annotation

  • modifier: DMS
  • processing: RNAFramework-v2.8.3
  • temperature: 24C
  • chemical: bicine:150mM(pH8.5), MgCl2:10mM

Citation

Kretsch RC, Xu L, Zheludev IN, Zhou X, Huang R, Nye G, Li S, Zhang K, Chiu W, Das R Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses. Proceedings of the National Academy of Sciences of the United States of America (2024) . doi:10.1073/pnas.2320493121 . PMID:38427602

Notes

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